Insulin Potentiation Therapy


Insulin potentiation therapy, or IPT therapy, represents a dramatic shift in the treatment of cancer. IPT utilizes the hormone insulin, which the body produces naturally, to potentiate or augment the delivery of chemotherapy medicine by making cancer cell membranes more permeable. The goal is to make pharmacological treatments more effective while reducing the harsh side effects.

How Does IPT Chemo Work?

Insulin potentiation therapy is also known as low-dose chemotherapy. This alternative cancer treatment effectively fights many types of cancers — without the side effects associated with traditional chemotherapy (nausea, hair loss, liver damage and more).

All cells depend on Insulin to help them absorb glucose (sugar) from the blood. The insulin attaches to the cells’ insulin receptors and acts like a key, opening channels in the cell wall that allow nutrients to enter. The glucose is transported across the cell membrane into the cell, where it is made into energy. Cancer cells have between 6 and 15 times more insulin receptors on their surface than normal cells have, which is why cancer cells compete better for food, absorbing the large amounts of glucose that help them grow.

During IPT chemo, insulin is administered to the patient, which decreases the body’s sugar level. Normal cells switch to metabolizing fat; but cancer cells, which live on sugar, respond to the insulin by opening all their membranes as they attempt to get more glucose. At this point, a low amount of chemotherapy is administered, followed by glucose. The cancer cells absorb the chemotherapy drugs along with the glucose, and the drugs poison and kill the cancer cells.

IPT Works with Low-Dose Chemotherapy

By targeting chemo drugs directly to cancer cells via insulin, smaller doses of these powerful drugs are required to kill the cancer cells. The most effective IPT treatments use only 4% – 10% of the standard amount of chemotherapy, and the fewer the chemo drugs, the fewer the nasty side effects. IPT is essential for patients who cannot tolerate the extreme side effects that accompany larger doses of chemotherapy drugs.

Additional Benefits of IPT Therapy
  • IPT helps larger concentrations of chemo drugs enter cancer cells. A Georgetown University Medical School study showed that methotrexate, a common chemotherapy drug, penetrates cancer cells 10,000 times faster when the cells were prepared with insulin, making IPT an effective cancer-fighting treatment option.
  • The insulin acts not only to deliver the chemo drugs to the cancer cells, but also to help these cells transition to their growth phase. When cancer cells are in this phase, they are more vulnerable to the effects of the chemo drugs, making IPT treatment even more productive.
  • Insulin potentiation therapy protects healthy cells. Chemo drugs do not enter healthy cells at the same rate because normal cells have fewer insulin receptors than cancer cells have. The chemotherapy drugs are successfully targeted to the cancer cells while having little effect on other cells, which helps to protect healthy cells and preserve the immune system.
  • IPT helps cancer patients maintain their appetite and metabolism, helping them to avoid the wasting stage that can accompany standard cancer treatments.
  • IPT may help the body to detoxify. When the cancer cells are killed, toxins are flushed into circulation and eliminated from the body.
IPT Therapy at Natural Horizons

Natural Horizons offers IPT, the alternative cancer treatment that is revolutionizing how medical scientists think about treating cancer. Researchers are still working to understand the underlying principles of this approach that allows chemotherapy to attack cancer cells by overwhelming them with food and insulin.

Dr. Joseph Shaw Jones, Medical Director at Natural Horizons, is one of 135 physicians in the world trained in this innovative alternative therapy. Dr. Jones has the specialized training and expertise to perform IPT cancer treatment. Only clinicians with extensive training in oncology and cancer treatment can determine whether IPT is right for a particular patient, and administer insulin potentiation therapy as needed to fight cancer without causing overwhelming side effects.


Dr. Shaw Jones is a medical doctor with extensive experience in natural forms of medicine and IPT, but he is not an oncologist. While the information on this site represents the opinions of Dr. Jones based upon his knowledge, experience and training as to safety and effectiveness of this treatment, these recommendations have not been reviewed by the U.S. Food and Drug Administration.

The drugs that are used in this protocol are approved for other uses by the FDA, either in the treatment of cancer at larger doses or for the treatment of diabetes, but their uses in this protocol are not FDA approved nor are they at this time recognized by the National Cancer Institute (NCI) or other medical societies involved in oncology. The use of insulin in this treatment is an off-label use, and the chemotherapeutic agents are those customarily used for specific tumors, but their use in low doses is outside recommended protocols. Studies in Mexico have been promising, but this research has not been subjected to sufficient validation in order to gain acceptance beyond a small community of physicians.

The material provided on this site is for educational purposes only, and any recommendations are not intended to replace the advice of your physician. You are encouraged to seek advice from a competent medical professional regarding the applicability of any recommendations with regard to your symptoms or condition.

It is important that you do not reduce, change or discontinue any medication or treatment without first consulting your physician

Begin Your Journey to Lifelong Wellness

Make an Appointment